Best Supplements for Anxiety & Stress: The Ultimate 2025 iHerb Guide 🌿🧘

Is your mind constantly racing? Do you feel a persistent sense of overwhelm, like you’re always “on” and can’t switch off? In our demanding world, these feelings are becoming the new normal. While some stress is unavoidable, chronic anxiety doesn’t have to be your reality.

A powerful way to manage stress is by supporting your body’s own calming systems. Your diet, exercise, and sleep are foundational, but targeted supplements can provide potent, direct support to your nervous system. They can help you build resilience, find focus, and finally feel a sense of calm.

This guide explores the best supplements for anxiety and stress on iHerb, explaining how they work and helping you choose the right tools for your personal “calm toolkit.”

How Supplements Can Fight Stress & Anxiety

Supplements for anxiety aren’t magic pills, but they are powerful allies. They work by interacting with your body’s stress-response system in several ways:

• Modulating Cortisol: Adaptogens like Ashwagandha can help balance the primary stress hormone, cortisol.
• Boosting Calming Neurotransmitters: Compounds like GABA and L-Theanine can increase the activity of brain chemicals that promote relaxation.
• Relaxing the Nervous System: Minerals like Magnesium play a direct role in soothing the nervous system and relaxing muscles.

The Top 5 Supplements for Anxiety & Stress on iHerb

Here are our top-rated, science-backed picks from iHerb to help you manage anxiety and find your calm.

1. Ashwagandha: The Stress Resilience Builder 💪

Why it’s essential: Ashwagandha is the king of adaptogenic herbs. It doesn’t just suppress stress; it helps your body adapt to it more efficiently. Regulating cortisol levels helps you feel less “frazzled” by daily pressures and prevents burnout.

The iHerb Advantage: NOW Foods Ashwagandha offers a potent, standardized extract to ensure you receive a consistent dose of withanolides, the active compounds. It’s a trusted, affordable option for building your baseline resilience to stress.

Best for: Chronic stress, feelings of overwhelm, and building long-term resilience.

➡️ Check Price on iHerb: NOW Foods, Ashwagandha, 450 mg

2. L-Theanine: The Calm Focus Creator 🍵

Why it’s essential: Ever wondered why green tea is both calming and clarifying? The answer is L-Theanine. This amino acid increases alpha brain waves, which are associated with a state of “wakeful relaxation.” It allows you to feel calm and focused without any drowsiness, making it perfect for daytime anxiety.

The iHerb Advantage: California Gold Nutrition’s L-Theanine features AlphaWave®, a patented, highly purified form of L-Theanine. This ensures maximum efficacy for reducing stress and improving cognitive function. It’s a must-have for social anxiety or pre-meeting jitters.

Best for: Daytime anxiety, promoting focus under pressure, and taking the “edge” off caffeine.

➡️ Check Price on iHerb: California Gold Nutrition, L-Theanine, 100 mg

3. GABA: The Brain’s Natural Brakes 🛑

Why it’s essential: GABA (Gamma-Aminobutyric Acid) is your brain’s primary inhibitory neurotransmitter. Think of it as the brake pedal that slows down racing thoughts and quiets an overactive mind. When GABA levels are low, it’s hard to relax and switch off. Supplementing can help restore this natural calming signal.

The iHerb Advantage: NOW Foods GABA provides a straightforward 750 mg dose of this key neurotransmitter. It’s particularly effective for those who struggle with cyclical, racing thoughts that prevent them from relaxing in the evening.

Best for: Racing thoughts, evening anxiety, and promoting a state of relaxation.

➡️ Check Price on iHerb: NOW Foods, GABA, 750 mg, 100 Veg Capsules

4. Magnesium Glycinate: The Ultimate Relaxation Mineral ✨

Why it’s essential: Stress rapidly depletes your body’s magnesium stores. This is a problem because magnesium is essential for regulating the body’s stress-response system and relaxing the central nervous system. Magnesium Glycinate is a superior, highly absorbable form that is gentle on the stomach and perfect for calming anxiety.

The iHerb Advantage: We’ve recommended it before in our guide to the best magnesium for sleep, and we’ll do it again. NOW Foods Magnesium Glycinate is a top-tier choice due to its high bioavailability and trusted quality, making it one of the best supplements for anxiety and physical tension.

Best for: Physical symptoms of anxiety (muscle tension), improving sleep, and restoring depleted mineral levels.

➡️ Check Price on iHerb: NOW Foods, Magnesium Glycinate, 180 Tablets

5. Lemon Balm: The Gentle Calming Herb 🍋

Why it’s essential: Lemon Balm is a gentle but effective herb from the mint family, traditionally used for centuries to soothe tension and calm the nerves. It works by supporting GABA levels in the brain, leading to a mild, natural sedative effect that reduces anxiety without heavy side effects.

The iHerb Advantage: Nature’s Way Lemon Balm offers a pure, simple herbal supplement that is perfect for those new to anxiety aids or who are sensitive to stronger formulas. It can be taken as needed or used to make a calming evening tea.

Best for: Mild anxiety, and nervous tension, and as a gentle sleep aid.

➡️ Check Price on iHerb: Nature’s Way, Lemon Balm, 1,500 mg, 100 Vegan Capsules

Building Your Calm Stack: How to Combine Supplements

You don’t have to choose just one! Stacking supplements can be very effective.

• For All-Day Resilience: Take Ashwagandha daily to build your foundation.
• For Daytime Focus: Add L-Theanine in the morning or before stressful events.
• For Evening Wind-Down: Use Magnesium Glycinate and GABA 1-2 hours before bed to quiet your mind and body.

Frequently Asked Questions (FAQ) ❓

Q: What are the best supplements for anxiety that don’t cause drowsiness? A: L-Theanine is the top choice for this. It promotes a state of “calm focus” without sedation. Rhodiola Rosea (an adaptogen) is another excellent option for improving focus under stress.

Q: Can I take Ashwagandha and L-Theanine together? A: Yes, they make a great combination. Ashwagandha builds long-term stress resilience, while L-Theanine provides acute, in-the-moment calming effects.

Q: How quickly can I expect to feel results? A: L-Theanine and GABA can often be felt within 30-60 minutes. Magnesium can also have a noticeable calming effect on the same day. Ashwagandha works cumulatively, with the best results often seen after 2-4 weeks of consistent use.

Q: Are these supplements addictive? A: The supplements listed here (Ashwagandha, L-Theanine, GABA, Magnesium, Lemon Balm) are not considered to be addictive and do not cause physical dependence.

Conclusion: Your Path to Peace

Managing anxiety is a journey, not a destination. By integrating the best supplements for anxiety and stress into a holistic lifestyle, you can provide your body and mind with the support they need to navigate modern life with more grace and ease. Start with one or two supplements from this list that resonate with your symptoms, and take the first step toward a calmer, more centred you.

(As an affiliate, we may earn a commission from qualifying purchases at no extra cost to you. We only recommend products we trust and have researched thoroughly.)

About the Author

This article was written and medically reviewed by the BellyBrainBed Editorial Team. Our team is composed of certified health coaches, nutritionists, and sleep science enthusiasts dedicated to providing accurate, evidence-based information to help you achieve optimal wellness. We believe in transparency and trust, and every piece of content is rigorously checked to meet our high E-E-A-T standards. [Learn more about our editorial process]